Cook the elbow macaroni according to package instructions until al dente. Drain and set aside.

In a large saucepan, melt the butter over medium heat. Once melted, whisk in the flour and cook for about 1-2 minutes until lightly golden.

Gradually whisk in the whole milk, stirring constantly until the mixture thickens and bubbles, about 5-7 minutes.

Remove the saucepan from heat and stir in the white cheddar cheese, mozzarella cheese, garlic powder, onion powder, salt, black pepper, and cayenne pepper (if using) until the cheese is completely melted and the sauce is smooth.

Add the cooked macaroni to the cheese sauce and stir until well combined.

Preheat your oven to 350°F.

Pour the mac and cheese mixture into a greased 9x13-inch baking dish. In a small bowl, combine the breadcrumbs and grated Parmesan cheese, then sprinkle evenly over the top of the mac and cheese.

Bake for 20-25 minutes or until the top is golden brown and the cheese is bubbly.

Let it cool for a few minutes before serving.