Name: Keto Spinach Artichoke Chicken Casserole for Cozy Nights
Prep time: 15 min
Cook time: 25 min
Total time: 50 min
Ingredients: 2 cups Cooked Chicken (Shredded or cubed, rotisserie chicken is convenient); 10 ounces Frozen Spinach (Well-drained); 1 cup Artichoke Hearts (Plain, canned or rinsed frozen); 8 ounces Cream Cheese (At room temperature); 1/2 cup Parmesan Cheese (Grated); 2 cups Mozzarella Cheese (Shredded, divided); 1/2 cup Sour Cream; 1/4 cup Heavy Cream (Can substitute with milk); 1/4 cup Mayonnaise (Optional); 2 cloves Garlic (Fresh minced); 1 teaspoon Salt (Adjust to taste); 1/2 teaspoon Pepper (Adjust to taste)

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As I opened my fridge in search of leftovers, I was met with a sudden craving for something comforting yet delicious. That’s when the idea struck me: a Spinach Artichoke Chicken Casserole. This creamy, cheesy delight reimagines a beloved dip into a satisfying keto-friendly main dish. In just a short time, you can whip this up for busy weeknights or meal prep, ensuring you have a hearty option ready to go. With tender shredded chicken and gooey mozzarella, this casserole isn’t just a crowd-pleaser; it’s also low carb, making it an ideal choice for those on a keto journey. Ready to elevate your weeknight dinners? Let’s dive into this delightful recipe together!

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Why is this casserole a must-try?

Creamy Indulgence: This Keto Spinach Artichoke Chicken Casserole brings the rich, comforting flavors of your favorite dip right to your dining table.

Quick & Easy: It’s a hassle-free recipe that simplifies weeknight cooking, providing a wholesome meal in under an hour.

Meal Prep Friendly: Perfect for busy days, you can prepare it ahead of time and simply bake when you’re ready to eat.

Low-Carb Goodness: With just 493 calories per serving, it fits perfectly within a keto lifestyle without sacrificing taste.

Crowd-Pleasing Flavor: Gooey mozzarella and savory chicken make for a family favorite that even non-keto eaters will love—much like my popular Broccoli Chicken Penne.

Versatile Twist: Get creative by adding your favorite veggies or swapping out chicken for turkey, keeping things exciting each time you make it!

Spinach Artichoke Chicken Casserole Ingredients

• Get ready to savor this delightful twist!

For the Casserole

Cooked Chicken – This provides protein and structure; feel free to use rotisserie chicken for convenience.
Frozen Spinach – A great source of greens and fiber; just make sure it’s well-drained to prevent excess moisture.
Artichoke Hearts – These add a unique texture and flavor; choose plain, canned, or rinsed frozen options.
Cream Cheese – Acts as the creamy base for your sauce; letting it reach room temperature will make mixing easier.
Parmesan Cheese – Elevates the flavor while adding body to the casserole.
Mozzarella Cheese – Provides that irresistible gooey topping; shredded is best for optimal meltability.
Sour Cream – Adds creaminess and a bit of tang to the mix.
Heavy Cream – Creates an ultra-rich sauce; if you prefer lighter, you can substitute it with milk.
Mayonnaise – Optional for extra creaminess, but highly recommended.
Garlic – Fresh minced garlic gives aromatic depth; don’t skip this essential ingredient.
Salt and Pepper – Essential for bringing all the flavors together; adjust to suit your taste.

Each of these components comes together to craft a delightful Spinach Artichoke Chicken Casserole that is sure to impress!

Step‑by‑Step Instructions for Spinach Artichoke Chicken Casserole

Step 1: Preheat the Oven
Start by preheating your oven to 375°F (190°C) to ensure it’s hot and ready for baking. This initial step is crucial for achieving that golden, bubbly top on your Spinach Artichoke Chicken Casserole, setting the stage for a perfect texture.

Step 2: Mix the Creamy Base
In a large mixing bowl, combine the room temperature cream cheese, sour cream, heavy cream, mayonnaise, minced garlic, salt, and pepper. Use a hand mixer or sturdy spatula to blend these ingredients until smooth and creamy—about 3-5 minutes. This base provides the rich, velvety sauce that makes the casserole delectable.

Step 3: Stir in the Remaining Ingredients
Next, fold in the cooked chicken, thoroughly drained frozen spinach, artichoke hearts, grated parmesan, and half of the shredded mozzarella cheese. Mix gently until all ingredients are evenly combined, ensuring each spoonful of the Spinach Artichoke Chicken Casserole is flavorful and packed with goodness.

Step 4: Transfer to Baking Dish
Carefully transfer the mixture into a greased 9″x13″ baking dish. Spread it out evenly using a spatula to ensure every corner is filled with the delicious chicken and spinach blend. This step is vital for even cooking, allowing all components to meld beautifully during baking.

Step 5: Add the Cheese Topping
Top the mixture with the remaining shredded mozzarella cheese, sprinkling it evenly across the surface. This layer will create that delightful, gooey melt that everyone loves. The gooey cheese topping is essential to achieving the perfect finish for your casserole.

Step 6: Bake to Perfection
Place the baking dish in the preheated oven and bake for 20 minutes. Then, increase the temperature to 400°F (204°C) and bake for an additional 5 minutes, or until the cheese tops are golden brown and bubbling. Keep an eye on it for that perfect, enticing crust!

Step 7: Cool and Serve
Once out of the oven, allow the Spinach Artichoke Chicken Casserole to cool slightly for about 10 minutes. This resting time lets the flavors settle and the casserole firm up a bit, making it easier to serve. Enjoy this hearty dish while warm for the ultimate comfort meal!

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Make Ahead Options

These Spinach Artichoke Chicken Casserole is perfect for meal prep, allowing busy home cooks to enjoy a delicious, hearty meal with minimal day-of effort. You can assemble the casserole up to 24 hours ahead; just cover it tightly with plastic wrap and refrigerate. For maximum freshness, ensure your spinach is well-drained to avoid excess moisture, which can make the casserole soggy. When you’re ready to bake, simply remove it from the fridge and let it sit at room temperature for about 20-30 minutes before popping it into the oven. This ensures the dish cooks evenly and comes out just as delicious as if it were made fresh! Enjoy the time-saving benefits of having this flavorful Spinach Artichoke Chicken Casserole ready to go whenever you need it.

Spinach Artichoke Chicken Casserole Variations

Feel free to explore these delightful twists on your casserole for a unique touch that tantalizes your taste buds!

Fresh Spinach: Substitute fresh spinach for frozen, using about 6-8 cups. It wilts beautifully, enhancing freshness and flavor.
Veggie Loaded: Incorporate diced sun-dried tomatoes or asparagus for added nutrition and vibrant bursts of flavor that brighten every bite.
Different Meat: Use cooked turkey instead of chicken for a delicious alternative. It brings a wonderful flavor without deviating from the overall comfort of the dish.
Cheesy Mix: Experiment with different cheese combinations, such as a blend of mozzarella and cheddar for a sharp, flavorful twist that will delight cheese lovers.
Spicy Kick: For those who enjoy a bit of heat, add crushed red pepper flakes or diced jalapeños. This addition will elevate your Spinach Artichoke Chicken Casserole to boldly savory heights.
Creamy Swap: Replace heavy cream with coconut cream for a dairy-free, richer option that adds a subtle sweetness without straying from the keto theme.
Nuts for Crunch: Toss in toasted pine nuts or walnuts before serving for a satisfying crunch that contrasts beautifully with the creamy filling.
Herb Infusion: Add fresh herbs like basil or thyme to the mix for a touch of aromatic freshness, reminiscent of herb gardens on warm summer days.

No matter how you choose to customize your casserole, I encourage you to explore flavors that excite you. And if you’re ever in need of more inspiration, check out my delicious Garlic Butter Chicken or the satisfying Spinach Tortellini Delights for cozy meal ideas!

Expert Tips for Spinach Artichoke Chicken Casserole

Drain the Spinach: Ensure the frozen spinach is well-drained to avoid a watery casserole that can affect the texture.
Mix Thoroughly: Take the time to mix the creamy base ingredients until smooth; this ensures every bite of the Spinach Artichoke Chicken Casserole is rich and flavorful.
Use Room Temperature Ingredients: Having your cream cheese at room temperature makes mixing a breeze and results in a creamier sauce without lumps.
Customize Your Cheese: Feel free to play with cheese varieties; switching to cheddar or adding more mozzarella can change the flavor profile delightfully.
Don’t Rush Cooling: Allow the casserole to cool slightly before serving; this helps it set, making for easier slices and better presentation.
Perfect for Freezing: This casserole freezes wonderfully, making it a great choice for meal prep. Just thaw in the fridge overnight and reheat when ready to feast!

What to Serve with Keto Spinach Artichoke Chicken Casserole

Cozy up your table with delightful additions that elevate this creamy casserole into a complete meal experience!

Garlic Bread: The crunchy exterior and warm, buttery garlic flavor offer a perfect contrast to the casserole’s creaminess, making each bite comforting.
Cauliflower Rice: Light and fluffy, this low-carb option serves as a neutral backdrop that absorbs the delicious cheesy sauce, blending perfectly with the dish.
Mixed Green Salad: A vibrant salad with crispy greens and a tangy vinaigrette introduces freshness and balances the richness of the casserole, enhancing your dining experience.
Roasted Brussels Sprouts: Their earthy flavor and slightly crispy texture complement the creamy casserole beautifully, adding depth to the meal that guests will rave about.
Baked Zucchini Fries: These crunchy, savory delights serve as a great side with a crispy texture that contrasts with the casserole’s softness, making dinner more fun!
Lemon-Infused Sparkling Water: A refreshing drink that cuts through the richness and adds a zesty sparkle to your meal, enhancing flavors without adding carbohydrates.

Enjoy exploring these delicious pairings that make a wholesome dinner even more delightful!

Storage Tips for Spinach Artichoke Chicken Casserole

Fridge: Store any leftovers in an airtight container for up to 3 days. Make sure the casserole is completely cooled before sealing to maintain freshness.

Freezer: Spinach Artichoke Chicken Casserole can be frozen for up to 3 months. Wrap it tightly in plastic wrap, then foil to prevent freezer burn.

Reheating: Reheat in the oven at 350°F (175°C) for 20-25 minutes or until heated through. If frozen, allow it to thaw in the fridge overnight before reheating for best results.

Meal Prep: If meal prepping, assemble the casserole in advance and keep it covered in the fridge for up to 24 hours before baking. This way, you have a delicious, ready-to-bake Spinach Artichoke Chicken Casserole waiting for you!

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Spinach Artichoke Chicken Casserole Recipe FAQs

What type of spinach should I use?
I recommend using frozen spinach for convenience. Make sure it’s thoroughly drained to avoid excess moisture in the casserole, which can lead to a watery texture. If you prefer fresh spinach, about 6-8 cups will make a great substitute, but keep in mind it will wilt down significantly.

How should I store leftovers?
Store any leftover Spinach Artichoke Chicken Casserole in an airtight container in the fridge for up to 3 days. Be sure the casserole is completely cooled before sealing to maintain its freshness and prevent sogginess.

Can I freeze this casserole?
Absolutely! You can freeze the Spinach Artichoke Chicken Casserole for up to 3 months. Just wrap it tightly in plastic wrap and then in foil to prevent freezer burn. For best results, thaw it in the refrigerator overnight before reheating in the oven at 350°F (175°C) for about 20-25 minutes.

What can I do if the casserole is too watery?
If you find that your casserole turns out watery, it could be due to excess moisture from the spinach or not enough baking time. To remedy this next time, make sure to drain your spinach thoroughly. You might also want to bake it a little longer to allow more moisture to evaporate.

Is this dish suitable for those with lactose intolerance?
For those with lactose intolerance, you can adjust the recipe by using lactose-free cream cheese and sour cream instead of regular. Additionally, opting for a lactose-free heavy cream will help make this dish suitable for your dietary needs without sacrificing the creamy texture.

Can I prepare this casserole in advance?
Yes, you can! If you’d like to prepare this Spinach Artichoke Chicken Casserole ahead of time, assemble it in a baking dish a day in advance, cover it tightly, and refrigerate. Just remember to let it sit at room temperature for 20-30 minutes before baking to ensure even cooking!